ea0068p36 | Abstracts | UKINETS2019
El Sayed Ahmed
, Boharoon Hessa
, Alsafi Ali
, Preitner Nadia
, Kosicka-Slawinska Monika
, Brady Angela
, Hill Peter
, Tan Tricia
Von Hippel-Lindau (VHL) disease is an inherited tumour syndrome, caused by a mutation in the VHL tumour suppressor gene encoding the VHL protein. Patients are prone to cysts and neuroendocrine tumours in the pancreas and other benign and malignant neoplasms. Pancreatic cysts occur in approximately 70% of VHL patients. We describe two cases of VHL disease with extensive multi-cystic changes affecting the whole pancreas, both patients had deletions of exon 23 of the VHL ge...