Endocrine Abstracts

Context: Autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy (APECED) is an autoimmune endocrinopathy with severe and unpredictable course. Previous studies have reported increased mortality in patients with APECED. However, the impact of APECED on mortality has not been previously determined.Objective: To systematically study overall and cause-specific mortality in patients with APECED. Design and Setting: A follow-up study of Fin...

Introduction: Autoimmunity is an important etiological factor of premature ovarian insufficiency (POI, menopause <40 years). It has been estimated that 4-50 % of POI cases are of autoimmune origin. Only a few studies, with sample sizes of dozens to hundreds POI cases, have investigated the prevalence of autoimmune diseases in women with POI. We aimed to assess in an essentially larger data set the prevalence of severe autoimmune diseases treated in tertiary care prior to P...