ea0041gp130 | Obesity | ECE2016
Kreutzer Carina
, Peters Sonke
, Schulte Dominik
, Turk Kathrin
, Wolff Stephan
, Rohr Axel
, Kerby Tina
, Riedel Christian
, van Eimeren Thilo
, Schreiber Stefan
, Laudes Matthias
Introduction: Obesity is associated with hypothalamic inflammation (HI) in animal models. While MRI studies in humans also found an increased intensity in the MBH in obese subjects, it remains unclear (1) if HI causes neuronal death and (2) if HI reverses during weight loss.Patients and methods: n=50 obese subjects and n=50 age- and sex-matched controls where examined. MRI scans including spectroscopy were performed. Also, detailed nutr...