ea0047oc4 | Spotlight on Neuroendocrine tumours | Theranostics2016
Azzouna Rana Ben
, Al-Shoukr Faisal
, Hyafil Fabien
, Rouzet Francois
, Guilloteau Denis
, Le Guludec Dominique
Introduction: DOTANOC is a largely used somatostatin analogue in NETs investigations. In NODAGANOC, the DOTA is replaced by NODAGA, a chelator derivative from NOTA which is the gold standard for Ga3+ and Cu2+ chelation because it forms more stable complexes than DOTA.[1] The aim of our study is to evaluate the affinity of NODAGANOC for somatostatin receptors (sst) and to develop a 68Ga and 64Cu labelled NODAGANOC for a fu...