Endocrine Abstracts

Introduction: Mechanism of pathogenesis of pituitary adenomas is still unknown. Gene expression differences in pituitary cells of different origin are not extensively described. Identification of genes specific for pituitary adenomas should enable better understanding of differences in their response to therapy, especially to radiotherapy.Aim: The aim of our study was to evaluate the correlation of coexpression of distinct pituitary adenoma genes based o...

Introduction: Pathogenesis of pituitary adenomas is largely unknown thus, identification of genes specific for various types of pituitary tumors should enable better understanding of their biology.The aim of our study was to analyze differences in gene expression between functional (FA) and non-functional (NFA) pituitary adenomas. For this goal, we considered folate receptor (FOLR1) shown by previous study (Evans et al. 2003) to be overexpr...