ea0081p10 | Adrenal and Cardiovascular Endocrinology | ECE2022
Backlund Nils
, Brattsand Goran
, Lundstedt Staffan
, Aardal Elisabeth
, Bartuseviciene Inga
, Katarina Berinder
, Burman Pia
, Eden Engstrom Britt
, Hoybye Charlotte
, Isaksson Anders
, Ragnarsson Oskar
, Ruetschi Ulrika
, Wahlberg Jeanette
, Olsson Tommy
, Dahlqvist Per
Background & Objective: Late night salivary cortisol (LNSC) and 1 mg overnight dexamethasone suppression test (DST) are two of the three recommended screening tests for Cushings syndrome (CS). The classical DST uses serum cortisol, but analysis of salivary cortisol and cortisone has shown high diagnostic accuracy at DST (1). Salivary cortisol can be analysed with immunoassays, which suffer from variable degree of cross reactivity with other steroids, or with LC-MS/MS...