ea0022s5.2 | Novel targets for thyroid cancer treatment | ECE2010
Santoro Massimo
There are four major types of thyroid cancer: well-differentiated papillary (PTC) and follicular (FTC) carcinoma, undifferentiated anaplastic carcinoma (ATC), and neural-crest derived medullary carcinoma (MTC). In the past two decades, some genetic lesions associated with these tumor types have been unveiled, with mutations in RET and BRAF, RAS and PPARγ, RAS, BRAF and PI3K/AKT, and RET, associated to PTC, FTC, ATC and MTC, respectively. PTC and FTC patients are treated b...