Searchable abstracts of presentations at key conferences in endocrinology

ea0029p924 | Female Reproduction | ICEECE2012

Propranolol prevents stress induced polycystic ovary syndrome

Silva Barros P. , Kalil B. , Anselmo-Franci J.

We have shown that repeated cold stress increases ovarian sympathetic tonus and induces typical polycystic ovary syndrome (PCOS) features. Lesion of the noradrenergic nucleus Locus Coeruleus decreases ovarian noradrenaline release and prevents stress-induced PCOS in rats exposed to chronic intermittent cold stress. The aim of this study was to assess whether the alterations on ovarian morphology, ovulation rate and hormonal secretion induced by cold stress could be prevented b...