Endocrine Abstracts

Background: Somatotroph PitNETs represent a polymorph group of GH-secreting pituitary neuroendocrine tumors with great variety of clinical presentation, which may graduate from totally silent without clinical and biochemical signs of hormonal hypersecretion to functioning with subtle or classic acromegaly symptoms. The grade of GH and somatostatin receptors expressoin as well as the other pituitary hormones and receptors co-expression may contribute to the tumor biological beh...