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ea0099oc4.3 | Oral Communications 4: Diabetes, Obesity, Metabolism and Nutrition | Part I | ECE2024

Nitrate-mediated dilation is impaired in people with type 1 diabetes and co-existent metabolic dysfunction-associated steatotic liver disease

Mertens Jonathan , Stoop Tibor , Francque Sven , De Block Christophe , Heuten Hilde

Introduction: The risk of cardiovascular disease (CVD) is increased in type 1 diabetes (T1D). Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to CVD, but evidence hereof is limited in people with T1D. Endothelial dysfunction is currently considered a key early event in the atherosclerotic process, but is never determined in people with T1D and co-existent MASLD.Methods: We measured flow-mediated dilation (FMD) and nitrate-media...

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Nitrate-mediated dilation is impaired in people with type 1 diabetes and co-existent metabolic dysfunction-associated steatotic liver disease

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