Searchable abstracts of presentations at key conferences in endocrinology

ea0090p497 | Thyroid | ECE2023

Course of Papillary Thyroid Carcinoma Diagnosed in Childhood and Adolescence and Followed Through Adulthood: Experience from a Tertiary Referral Center

Hacisahinogullari Hulya , Inan Balci Elif , Yenidunya Yalin Gulsah , Soyluk Selcukbiricik Ozlem , Bas Firdevs , Kubat Uzum Ayse , Poyrazoglu Sukran , Gul Nurdan

Introduction: Differentiated thyroid cancer accounts for 1.5% of all pediatric malignancies. Papillary thyroid cancer (PTC) is the most common subtype and is associated with more advanced disease at diagnosis compared to adults. The aim of this study was to identify long-term outcomes of pediatric PTC.Methods: Records of 30 patients with PTC diagnosed in childhood and adolescence and followed up at Istanbul Faculty of Medicine were reviewed retrospective...

ea0090ep1154 | Late Breaking | ECE2023

Prevalence, patterns, and characteristics of hypertension diagnosis and management in patients with Turner syndrome; Descriptive analysis of real-world data from the International-Turner Syndrome registry

Apsara Dilrukshi Mathara Diddhenipothage Shani , Beck Katharina , G K Amiyangoda C , Bryce Jillian , Cima Luminita , De Groote Katya , Deyanova Yana , Globa Eugenia , Herrmann Gloria , Juul Anders , Sophie. L Kjaer Anna , Tonnes Pedersen Pedersen Anette , Poyrazoglu Sukran , Probst-Scheidegger Ursina , C.J Sas Theo , Nimali Seneviratne Sumudu , Witczak Justyna , Orchard Elizabeth , Tomlinson Jeremy , Ahmed Faisal , Turner Helen

Introduction: Hypertension is common in patients with Turner Syndrome (TS), and they appear to have an increased predisposition with various proposed disease related factors; sex hormone imbalance, aortopathy, increased activation of the renin-angiotensin-aldosterone system, insulin resistance, growth hormone deficiency/resistance, adverse imprinting during fetal life and renal malformations. Despite high susceptibility and unique challenges in managing hypertension in this gr...

ea0094op3.1 | Reproductive Endocrinology | SFEBES2023

Are we giving enough attention to blood pressure control in turner syndrome? : Data from the international turner syndrome (I-TS) registry

Mathara Diddhenipothage Shani A.D. , Beck Katharina J. , Amiyangoda C G K , Bryce Jillian , Cima Luminita , De Groote Katya , Deyanova Yana , Globa Evgenia , Herrmann Gloria , Juul Anders , Sophie L. Kjaer Kjaer Anna , Tonnes Pedersen Anette , Poyrazoglu Sukran , Probst-Scheidegger Ursina , Sas Theo C.J. , Fica Simona , Nimali Seneviratne Sumudu , Karolina Witczak Justyna , Orchard Elizabeth , Tomlinson Jeremy W. , Faisal Ahmed S. , Turner Helen E

Introduction: Cardiovascular disease is the commonest cause of death (absolute-excess-risk:41%) in Turner Syndrome (TS). Hypertension is a major risk for circulatory-disease (up to 60%) and a key modifiable-risk factor of aortopathy, ischemic heart disease and stroke in TS. There is no current consensus for hypertension diagnosis/management in TS.Methods: Retrospective multi-centre observational study of patients aged &#...

ea0078p1 | Adrenal | BSPED2021

Analysis of therapy monitoring in the International Congenital Adrenal Hyperplasia Registry

Lawrence Neil , Bacila Irina , Dawson Jeremy , Bryce Jillian , van den Akker Erica , Sartori Sanchez Bachega Tania Aparecida , Baronio Federico , Birkebaek Niels Holtum , Bonfig Walter , Claahsen Hedi , Correa Costa Eduardo , Devries Liat , Elsedfy Heba , Guven Ayla , Hannema Sabine , Iotova Violeta , van der Kamp Hetty J , Clemente Leon Maria , Lichiardopol Corina Raducanu , Milenkovic Tatjana , Neumann Uta , Nordenstrom Ana , Poyrazoglu Sukran , Probst-Scheidegger Ursina , De Sanctis Luisa , Thankamony Ajay , Vieites Ana , Yavas Zehra , Ahmed Faisal , Krone Nils

Background: Congenital Adrenal Hyperplasia (CAH) requires exogenous steroid replacement and can be monitored with 17-OH Progesterone and Androstenedione. We reviewed real world data to evaluate these markers in relation to hydrocortisone dose in patients treated in 21 centres throughout 14 countries.Method: Retrospective cohort study using pseudonymised data from patients with 21α-Hydroxylase Deficiency recorded in the International Congenital Adren...

ea0059p181 | Reproduction | SFEBES2018

Gonadectomy for adults with DSD conditions at risk of hypogonadism in the international disorders of sex development registry

Herald Angela Lucas , Kyriakou Andreas , Bryce Jillian , Rodie Martina , Acerini Carlo , Arlt Wiebke , Balsamo Antonio , Baronico Federico , Bertelloni Silvano , Brooke Antonia , van der Grinten Hedi Claahsen , Cools Martine , Darendeliler Feyza , Davies Justin H , Desloovere An , Ellaithi Mona , Fica Simona , Gawlik Aneta , Guran Tulay , Hannema Sabine , Hiort Olaf , Holterhus Paul-Martin , Iotova Violeta , Jennane Farida , Lachlan Katherine , Li Dejun , Lisa Lidka , Mazen Inas , Mladenov Wilchelm , Mohnike Klaus , Nedelea Lavnia , Niedziela Marek , Nordenstrom Anna , Poyrazoglu Sukran , Rey Rodolfo , Tadokoro-Cuccaro Rieko , Weintrob Naomi , Ahmed Syed Faisal

Introduction: Disorders of Sex Development (DSD) can be associated with an increased risk of germ cell tumours depending on the underlying diagnosis. To date however knowledge regarding the indications and timing of gonadectomy is lacking.Methods: The I-DSD Registry was interrogated for anonymised information regarding the diagnosis, karyotype, sex of rearing and timing of gonadectomy, if undertaken, of all individuals of any karyotype who were over the ...

ea0094p161 | Adrenal and Cardiovascular | SFEBES2023

An international study of the association between local health care resources and acute adrenal insufficiency events in children with congenital adrenal hyperplasia

Tseretopoulou Xanthippi , R Ali Salma , Bryce Jillian , Nadia Amin , Atapattu Navoda , Bachega Tania , Baronio Federico , H Birkebaek Niels , Bonfig Walter , Claahsen-Van der Grinten L. Hedi , Cools Martine , de Sanctis Luisa , de Vries Liat , Elsedfy Heba , E Flueck Christa , Fu Antony , Guaragna-Filho Guilherme , Guran Tulay , Guven Ayla , E Hannema Sabine , Iotova Violeta , Konrad Daniel , Lenherr-Taube Nina , Korbonits Marta , P Krone Nils , Krone Ruth , Leka-Emiris Sofia , Lichiardopol R Corina , Luczay Andrea , L Markosyan Renata , Mazen Inas , Milenkovic Tatjana , Mohnike Klaus , Neumann Uta , Niedzela Marek , Nordenstrom Anna , Phan-Hug Franziska , Poyrazoglu Sukran , Probst Ursina , Randell Tabitha , Vieites Ana , Russo Gianni , Thankamony Ajay , van den Akker Erica , van Eck Judith , van der Kamp Hetty , G Wasniewska Malgorzata , Ahmed Syed Faisal

Background: The reported occurrence and management of acute adrenal insufficiency–related adverse events in children vary widely between centres and may depend on available resources.Methods: Real world data from the I-CAH Registry from 44 centres [32 from high income (HIC) and 12 from low/middle income (LMIC) countries] and a total number of 607 children were linked to the results of a health care survey of local r...

ea0103oc5.5 | Endocrine Oral Communications 1 | BSPED2024

Glucocorticoid replacement therapy in congenital adrenal hyperplasia and its associations with growth outcomes - real world data analysis from an international cohort of 1500 patients

A Bacila Irina , Lawrence Neil R. , Balagamage Chamila , Bryce Jillian , Ali Salma R. , Alimussina Malika , Chen Minglu , Arya Ved Bhushan. , Atapattu Navoda , Bachega Tania , Barat Pascal , Baronio Federico , Bertelloni Silvano , Birkebaek Niels , Bonfig Walter , Bruin Christiaan de. , - van der Grinten Hedi Claahsen. , Cools Martine , Costa Eduardo , Crowne Elizabeth , Davies Justin H. , Debono Miguel , Vries Liat de. , Kubat Katja Dumic. , Elsedfy Heba , Evliyaoglu Olcay , Flueck Christa , Gazdagh Gabriella , German Alina , Gevers Evelien F. , Globa Evgenia , Guran Tulay , Guven Ayla , Guazzarotti Laura , Hannema Sabine , Hatipoglu Nihal , Janus Dominika , Kamp Hetty van. de. , Karabouta Zacharoula , Krone Ruth E. , Leka-Emiri Sofia , Taube Nina Lenherr. , Lichiardopol Corina , Hassan Mona Mamdouh. , Marginean Otilia , Markosyan Renata , Mazen Inas , Miles Harriet , Mitchell Anna L. , Mohnike Klaus , Neumann Uta , Niedziela Marek , Nordenstrom Anna , O'Connell Susan M. , Phan-Hug Franziska , Poyrazoglu Sukran , Probst-Scheidegger Ursina , Rey Rodolfo , Russo Gianni , Salerno Mariacarolina , Sanctis Luisa de. , Seneviratne Sumudu N. , Segev-Becker Anat , Shenoy Savitha , Skae Mars , Thankamony Ajay , Ucar Ahmet , Utari Agustini , Vieites Ana , Wasniewska Malgorzata , Ahmed S Faisal. , Krone Nils P.

Background and Aim: Previous research using data from the I-CAH registry showed wide variation between countries in the provision of glucocorticoid (GC) replacement in congenital adrenal hyperplasia (CAH). In this study, we aimed to establish the impact of different GC doses on height and weight in children and young people with CAH.Methods: Data from children with CAH recorded in the I-CAH registry since 2003 was collected, providing a cohort of 1522 pa...