ea0073pep4.1 | Presented ePosters 4: Reproductive and Developmental Endocrinology | ECE2021
Haverinen Annina
, Luiro Kaisu
, Szanto Timea
, Kangasniemi Marika
, Hiltunen Leena
, Sainio Susanna
, Piltonen Terhi
, Lassila Riitta
, Tapanainen Juha
, Heikinheimo Oskari
ObjectiveTo compare the effects of combined oral contraceptives (COCs) containing estradiol valerate (EV) and dienogest (DNG) with ethinyl estradiol (EE) and DNG on biomarkers of coagulation: thrombin generation (TG), prothrombin fragments F1+2 (F1+2) and D-dimer (D-Di). A DNG-only preparation was included as a control.BackgroundCOC use increases the risk of venous thromboembolism (VTE) 2-6-fold compa...