ea0063p1066 | Pituitary and Neuroendocrinology 3 | ECE2019
Anand Gurpreet
, Bernays Rene
, Neidert Marian
, Regli Luca
, Sze Lisa
, Tschopp Oliver
, Zwimpfer Cornelia
, Schmid Christoph
Background, aims: Acromegaly is caused by excessive growth hormone (GH) secretion, usually by a pituitary adenoma. Surgical removal of the GH-producing adenoma is the most effective treatment. Drug treatment is second-line option. Earlier work suggested Soluble (s)Klotho levels to be a supplementary biomarker to IGF-1. We tested whether IGF-1 and sKlotho serum levels show a concomitant reduction under medical treatment. If yes, is the extent of reduction in serum IGF-1 and sKl...