ea0094p73 | Metabolism, Obesity and Diabetes | SFEBES2023
Ramburuth Vivek
, Umer Reham
, PV Vegesna Ram
, V Sagi Satyanarayana
, O Oyibo Samson
, Z Htun Kyaw
Introduction: Pembrolizumab is an immune checkpoint inhibitor (ICI) used to treat advanced cancers. While improving survival rates, ICIs also cause immune-related adverse events (IRAEs). The endocrine system remains the most vulnerable to IRAEs: thyroid involvement is the commonest while pancreatic involvement is rare, affecting less than 1% of individuals. Risk factors for IRAEs include, personal or family history of autoimmune conditions, presence of another...