ea0012s20 | Cell-cell interactions in the regulation of endocrine cell function | SFE2006
Sharpe RM
, Atanassova N
, De Gendt K
, Verhoeven G
, Tan KAL
, Saunders PTK
, Scott H
The two primary functions of the adult testis (sperm production and hormone production) need to be co-ordinated because sperm production is completely dependent on appropriate hormone (primarily testosterone) production. However, it is equally evident from animal studies that Leydig cell (LC) development and function are also affected by developmental and functional status of the seminiferous tubules. For example, development of the adult LC population is dependent on reduced ...