Endocrine Abstracts

Introduction: Multiple endocrine neoplasia syndrome type 1 (MEN-1) is an autosomal dominant disorder caused by germline mutations in the MEN1 gene encoding menin. MEN1 mutations are mainly represented by deletions/insertions, nonsense, splice site or missense mutations and can be detected by DNA sequencing. MEN-1 generally includes parathyroid, adenohypophysis, and pancreatoduodenal neuroendocrine tumors.Clinical Case: Patient S., 26-ye...