ea0020p545 | Neuroendocrinology, Pituitary and Behaviour | ECE2009
Biermasz Nienke R
, Wassenaar Moniek J E
, van der Klaauw Agatha A
, Pereira Alberto M
, Smit Johannes W A
, Roelfsema Ferdinand
, Wolterbeek Ron
, Kroon Herman M
, Kloppenburg Margreet
, Romijn Johannes A
Objective: To identify factors influencing the development of osteoarthritis during long-term control of acromegaly, focusing on disease specific parameters, growth hormone (GH) and insulin-like growth factor I (IGF-I) concentrations and duration of disease, adjusted for the well-known determinants of primary osteoarthritis.Design: Follow-up study.Methods: We studied 67 patients, with adequate biochemical control of acromegaly for ...