ea0029p1476 | Pituitary Clinical | ICEECE2012
Burt M
, Mangelsdorf B
, Whiting M
, Rogers A
, Ho J
, Inder W
, Doogue M
Measurement of plasma cortisol by immunoassay after ACTH124 stimulation is used to assess the hypothalamicpituitaryadrenal (HPA) axis. Liquid chromatographytandem mass spectrometry (LCMS/MS) has greater specificity and equilibrium dialysis allows measurement of free plasma cortisol. We investigated whether measuring cortisol by LCMS/MS improves the sensitivity of ACTH124 stimulation testing in pituitary patients. ...