Endocrine Abstracts

Background: Sleep loss is increasingly common in the western world and has been shown to be associated with an increased risk of diabetes mellitus and obesity.Objective: We hypothesised that short term sleep loss results in a diabetogenic metabolic status during carbohydrate challenge at a breakfast buffet.Subjects and methods: Fifteen healthy, normal-weight young men were studied in randomized balanced order on the subsequent morn...

Introduction: The thyroid hormone (TH) status is routinely assessed by thyrotropin (TSH) and thyroxine (T4). Both biomarkers are mainly regulated by thyroid hormone receptor beta, whereas many peripheral organs employ the alpha receptor. Serum CD5L is a liver-derived protein under control of both TH receptor isoforms, but the data base is small [1]. An additional biomarker of TH status is needed in particular during pregnancy, where the routine biomarkers become dynamically di...