ea0026p332 | Obesity | ECE2011
van der Spek R
, Kervezee L
, La Fleur S
, Fliers E
, Kalsbeek A
Background: Shift workers and rodents with clock gene mutations show increased risk of metabolic syndrome and type 2 diabetes (T2DM). Conversely, obesity and T2DM are related to circadian disturbances in humans and rodents. The circadian release of adipokines from white adipose tissue (WAT) plays a pivotal role in energy metabolism. Its regulatory mechanism is unclear at present.Aim: To determine the daily expression patterns of genes involved in circadi...