Endocrine Abstracts

Aim: The main aim of this study was to examine the association of glucose and sodium level with diagnosis and disease outcome of critically ill patients.Patients and Methods: The glucose and sodium concentration of 283 patients admitted in critical condition to the Intensive Care Unit of the Department of Internal Medicine in a period from 1 November 2015 to 28 February 2017 were reviewed.Results: Most common diagnoses in criticall...

Objective: Primary hyperparathyroidism (PHPT) is a clinical condition characterized by hypercalcemia-specific symptoms and signs caused by excessive secretion of parathormone. After the evaluation of blood calcium measurements within routine tests, the frequency of hyperparathyroidism increased and there is a marked decrease in the frequency of classical symptoms and signs. Recently, most PHPT cases are detected in the asymptomatic period, and which of these asymptomatic patie...

Research Objectives: To investigate adrenal tumors of patients operated on at the Osijek Clinical Hospital from 2016 to 2019 to examine the location and histopathological findings of the tumors, and to determine whether there is a difference in the age and gender of the subjects.Study design: Cross-sectional study with historical data.Patients and Methods: The subjects were patients of both sexes diagnosed with adrenal tumors who u...

Background and Aim: The triglyceride glucose (TyG) index has been proposed as a marker of insulin resistance. This study aims to evaluate the utility of the TyG index in routine practice for predicting diabetes, prediabetes, and metabolic dysfunction-associated fatty liver disease (MAFLD) in obese individuals.Methods: The study retrospectively analyzed data from obese individuals at our outpatient clinic. The study recorded patient characteristics such a...

Research objective: To examine the frequency of chronic complications of type 2 diabetes with regard to age, sex, duration of diabetes and glucoregulation.Subjects and methods: The research included 78 subjects of both sexes with a diagnosis of type 2 diabetes treated in the Health Center of the Osijek-Baranja County. The following data were collected: gender, age, duration of diabetes, type of diabetes therapy and HbA1c, and complications of diabetes.</...

Background: Genomic structural variants (SVs) encompass a large portion of mutations driving cancer progression, however, there is a paucity of data regarding such drivers in metastatic neuroendocrine tumor (mNET). Existing studies have focused on short-read sequencing of primary NET samples, which can detect single nucleotide variants, but are unable to identify larger SVs. Such studies have demonstrated a low rate of genetic mutations. Optical genome mapping (OGM) represents...

Aim: To determine whether there is any factor that can predict sufficient results in second thyroid fine-needle aspiration biopsy (FNAB) after first nondiagnostic cytological result.Materials and method: Nodules with non-diagnostic result after first FNAB were included and separated into two groups as sufficient (Group-1) and insufficient (Group-2) second FNAB. Results: Second FNAB was performed on 643 nodules of 443 patients with ...

Introduction: The frequency of thyroid surgery for suspected malignancy but postoperative resulted with benign pathology tends to increase in the worldwide. Therefore, additional preoperative markers are needed to prevent excessive surgery. Neopterin is a new molecule secreted by monocytes and macrophages and indicates the activation of cellular immunity. Therefore it can be used as a marker of immune activation. We aimed to evaluate the diagnostic value of serum neopterin lev...

Objective: While postoperative hypoparathyroidism can usually be controlled with elemental calcium (Ca) and calcitriol therapy, rarely this treatment may be inadequate and teriparatid therapy may be used as an alternative. In the literature, it is reported that teriparatid therapy is effective and reliable in the treatment of patients with postoperative hypoparathyroidism, as well as improving quality of life and reducing the frequency of hospitalization. In this report, we pr...