Endocrine Abstracts

Introduction: The association of multi-organ autoimmune diseases is described. We report a case of association between Latent autoimmune diabetes in adults (LADA) and systemic scleroderma (SSc), which remains a rarely reported entity in the literature.Observation: 38-year-old female patient, followed for systemic scleroderma with digestive and pulmonary involvements. The patient presented a dysphagia to solids with dyspnea installed in the last 2 months,...

Introduction: Adrenal insufficiency is rarely diagnosed during pregnancy. In the absence of treatment it is associated with high maternal-foetal morbidity and mortality. We report the case of a twenty-one years old female patient, diagnosed with adrenal insufficiency during a diabetic pregnancy of 12 weeks of gestation.Observation: Twenty-one years old female patient, diagnosed with type 1 diabetes since the age of 15, Referred to our department for the ...

Introduction: Mitochondrial diabetes represents about 1% of diabetes but still very often misunderstood. The most frequent mutation is 3243A >G of the mtDNA, which is responsible for the maternally inherited diabetes and deafness syndrome (MIDD). We report an observation of a patient with strong suspicion of mitochondrial diabetes.Case presentation: 43-year-old female patient, with diabetes for 5 years on an Insulin Therapy.Anamnesis:&hypen;&...

Introduction: Insulin resistance is one of the characteristic abnormalities of type 2 diabetes. Recently it has been recognized that type 1 diabetes may also present with insulin resistance of varying intensity. We report a case of insulin resistance in a patient with type 1 diabetes.Observation: The patient was 23 years old, with a history of type 1 diabetes since the age of 20, with positive antibodies against GAD (glutamate acid decarboxylase), reveal...

Introduction: Type 1 diabetes is accompanied by a high frequency of autoimmune diseases.The aim: of this study is to determine the different epidemiological, clinical, immunological and therapeutic aspects of Type 1 Diabetes in Autoimmune Polyendocrinopathy and to analyze the results obtained.Patients and methods: This is a retrospective study of 44 patients with type 1 diabetes, suffering from Autoimmune Polyendocrinopathy and fol...

Introduction: Compared to normal population, patients with neurofibromatosis are at higher risk for the development of benign and malignant tumors. Pheochromocytomas are relatively rare in neurofibromatosis type 1 (NF1), and malignant ones are even rarer.Aim of the presentation: Our aim was to report a malignant pheochromocytoma with multiple metastases in a patient with NF1.Case report: A male patient aged 23 years old, with lapar...

Introduction: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor that arises from the parafollicular C-cells of the thyroid gland with a tendency to regional and distant metastases. It is a rare tumor, making up about 3% of all thyroid malignancies. MTC occurs in both heritable and sporadic forms, early diagnosis is important as it can improve treatment outcomes. We report a case of metastatic medullary thyroid cancer with both diagnostic and therapeutic challenges. <...

Hypoglycemia in non-diabetic patients is a rare event, and autoimmune hypoglycemia with the presence of positive anti-insulin antibodies is even rarer.We report the case of a 15 years old non diabetic female patient, she was referred to our hospital for recurrent hypoglycemia for 2 weeks before admission to hospital, these are severe hypoglycemia with impaired consciousness. The first step was to eliminate the general causes and factitious hypoglycemia. ...

Introduction: Pituitary adenomas are rare in infants and adolescents. Prolactinomas account for 50% of these pituitary adenomas. In adolescent girls, it is usually a microprolactinoma revealed by puberty delay or amenorrhea. We report a rare case of a macroprolactinoma in an adolescent girl revealed by visual impairment.Case presentation: A 15-year-old adolescent girl presented with loss of vision over a long period of time. Magnetic resonance imaging re...

Introduction: McCune-Albright syndrome (MAS) is a rare, Mosaic genetic (Lethal in the homozygous state) but non-hereditary disorder. The diagnosis is most often made in childhood, the management is multidisciplinary and includes several aspects. We report a case of Mc Cune Albright syndrome and the various difficulties encountered in its management.Case report: A, H 22 years old, at the age of 6 months presented skin macules. At the age of 3 years he dev...