Endocrine Abstracts

Introduction: Lymphocytic hypophysitis is a rare inflammatory disease of the pituitary gland of autoimmune origin, related to a diffuse infiltration of the pituitary gland sometimes leading to severe hypopituitarism. It is frequent in pregnant or postpartum women.Case report: A 28 year old female patient, followed up for pituitary microadenoma with prolactin for 5 years under dostinex 1 tablet/week who reported headaches with visual acuity decrease with ...

Introduction: Medical treatment of acromegaly with somatostatin analogues (SAs) has been used for a long time and is a well-established treatment in cases where surgery, which is the first-line treatment, is impossible or inadequate. We report a case of acromegaly under control after initiation of Lanreotide.Observation: Patient aged 59 years, referred for acromegaloid dysmorphic syndrome initially with tumor syndrome with IGF1 workup at 729 ng/mL (norma...

Introduction: Polyuro-polydipsia syndrome (PPS) is defined by urine excretion rate more than 3L per day, associated with a parallel increase in oral fluid intake. It poses problems of positive and etiological diagnosis. We discuss in this observation the modalities of exploration of PPS and its main etiologies.Case report: A 60-year-old patient, diabetic for 10 years, controlled on metformin, admitted for PPS evolving for 37 years. Clinical examination w...

Introduction: Steinert’s myotonic dystrophy (SMD) is a neuromuscular disorder with a multisystem distribution. It is a genetic disease with autosomal dominant transmission. It may be associated with various endocrine disorders.Observation: We report the case of a 47-year-old patient followed for DM since the age of 18, diabetic under insulin therapy for 20 years, hypertensive for 1 year under losartan 50 mg/d who was referred to us for evaluation of...

Introduction: Patients with PTC usually have excellent outcomes with appropriate therapy, while up to 30% of patients present with aggressive disease, including patients with locoregional recurrence and distant metastasis.The aim: Of this study is to analyze the characteristics of patients with papillary carcinoma of the thyroid with locoregional and distant recurrences.Résults: We included 12 cases of locoregional and distant...

Pendred syndrome, an autosomal recessive disorder, is the most common syndromal form of hearing loss and involves abnormalities of the cochlea, varying degrees of sensorineural hearing loss and diffuse thyroid enlargement/goiter. We describe a case of a delayed diagnosis of Pendred syndrome. The patient is a 30 years female who had a history of total thyroidectomy 13 years ago. And presented when aged 30 with a cervical abscess of ectopic thyroid under the submaxillary gland. ...

Introduction: Wernicke’s encephalopathy is a rare neurological disorder initially described in alcohol-dependent and malnourished patients. It is characterised by confusion, ataxia and nystagmus. It is caused by thiamine deficiency. We report the case of a patient with hyperemesis gravidarum and hashitoxicosis complicated by Wernicke’s encephalopathy Observation: A 22 year old patient, 1G0P, without any particular pathological history, was admi...

Introduction : Jougerot –sjogreen syndrom is an auto-immune exocrinopathy secondary to the interaction between a favorable ground and environmental factors that can lead to the disease. Thyroiditis can precede sjogreen’s syndrom or follow it, just as the two diagnoses can be made at the same time.Case report : 46-year-old female patient, type 2 diabetic on oral antidiabetic 2g/d, followed for sjogreen jougerot syndrom retained in the face of oc...

Introduction: Parkinson’s disease (PD) is one of the most common neurodegenerative disorders characterized by bradykinesia, tremor, rigidity and postural instability as well as neurocognitive impairment and depression. Studies found a significant association between thyroid dysfunction and an increased risk of PD. We report the case of a patient treated for PD who had also Hashimoto’s thyroiditis, and we discuss the association of thyroid dysfunction with risk of PD....

Introduction: Hepatic encephalopathy is a neuropsychological syndrome complicating a chronic liver disease (cirrhosis), rarely acute (fulminant hepatitis). We report the case of a patient with Graves’ disease who suddenly presented with hepatic encephalopathy. Case Report: S.B., a 48-year-old woman followed for Graves’ disease treated with antithyroid drugs and also presenting vitiligo, was admitted to our facility for a relapse of Graves’...