Endocrine Abstracts

Introduction: Excess weight has become a major public health problem. Type 2 diabetes and obesity are known risk factors for kidney disease. The aim of this study is to determine the effect of obesity on glomerular filtration rate (GFR) and microalbiminuria in patients with diabetes.Methods: This is a descriptive cross-sectional study conducted over three years in obese and type 2 diabetic patients hospitalized in the Endocrinology and Diabetology Depart...

Introduction: – Sheehan syndrome (SS), or postpartum pituitary necrosis, is a rare but potentially serious complication of postpartum. – SS remains an important cause of hypopituitarism in Morocco.– The aim of this study is to evaluate the metabolic profile of patients with SS.Materials and methods: – This is a retrospective descriptive study conducted in the endocrinology department, spread over a period of 12 years, between the year...

Introduction: Sheehan syndrome (SS), or postpartum pituitary necrosis, is a rare but potentially serious complication of postpartum. we describe a patient whose diagnosis of sheehan’s syndrome was delayed and revealed by a cardiovascular collapse.Case report: A 36 year old femele patient, admitted to the intensive care unit in a state of septic shock due to pyelonephritis, was intubated, ventilated and put on noradrenaline in SAP and antibiotic ther...

Introduction and Backgrounds: Pituitary adenomas emerge from the adenohypophysis and are confined to the region of the sella turcica, however, other sites may be involved as a result of extension infiltration, or ectopic location, the ectopic involvement of the sphenoid is rare. Case Report: Our case illustrated a woman patient with an ectopic invasive macroprolactinoma diagnosed as a chordoma of the skull base. In Our case, the first histological examin...

Introduction: The corpus callosum is the most important of the interhemispheric commissures, its fibers called callosal radiations have a transverse direction. They connect different points of the neocortex. The corpus callosum represents the neopallial commissure; it has indeed a phylogenetic development modeled on that of the neocortex. Hypoplasia of the corpus callosum is included in a rare polymalformative syndrome characterized by agenesis of the corpus callosum (CC), dis...

Introduction: Primary hyperparathyroidism and prolactinoma can be associated as part of a MEN1. However, the association of the two pathologies can also be seen outside of a syndrome predisposing to endocrine tumors. Case presentation: F.L., a 33-year-old woman followed for end-stage renal failure, during her follow-up hyperparathyroidism was discovered without any idea of the culprit and the victim: is the renal failure secondary to hyperparathyroidism ...

Introduction: Antenatal treatment with dexamethasone in pregnancies affected by congenital adrenal hyperplasias (CAH) therefore suppresses fetal androgen production and prevents virilisation of female infants. Antenatal DXM is reported to be efficacious, preventing or ameliorating virilisation in 80–85% of cases.Case report: 23-year-old patient pregnant at 6 weeks, not known of having congenital adrenal hyperplasia (CAH), concept of consanguineous m...

Introduction: Sexual differentiation depends on a succession of events, each stage of which may be the site of abnormalities resulting in sexual ambiguitý. Case report: 17-year-old female patient, consults for primary amenorrhea. On physical examination the morphotype is female, height is normal, secondary sexual characteristics are Tanner stage 1 with sexual ambiguitý Prader stage 4, No palpable testes with a subpenile Orifice. Pelvic ultrasou...

Introduction: The treatment of Graves’ disease is represented principally by anti-thyroid drugs, radioiodine ablation or thyroidectomy. Methimazole is the most used drug for the initial treatment. It is rare to encounter patients with resistant hyperthyroidism despite high doses of MMI.Case presentation: A 41-year-old woman was referred to our unit for resistant thyrotoxicosis. She had a confirmed Graves’ disease with positive serum Trab. Whils...

Introduction and Backgrounds: Myxedema coma is a severe life threatening form of decompensated hypothyroidism which is associated with a high mortality rate. Infections and discontinuation of thyroid supplements are the major precipitating factors. It’s characterized by a decreased mental status, hypothermia, bradycardia, hypotension, and hypoventilation. Very few cases of Myxedema coma have been reported till date, actual prevalence is unclear with the estimated incidenc...