Endocrine Abstracts

However ACTH secreting adenomas are one of the most common functional pituitary tumors, subtypes such as Crooke cell corticotroph adenoma(CCCA) are relatively rare. We present here a patient with CCCA who had severe hypercortisolism mimicking ectopic ACTH syndrome. A 69 years old female patient admitted to emergency department after a fall. On cranial MRI,’a 3.5x2.5x3cm mass appearance with a sellar-suprasellar location, which is compressing the optic chiasm, expanding th...

Introduction: The frequency of thyroid surgery for suspected malignancy but postoperative resulted with benign pathology tends to increase in the worldwide. Therefore, additional preoperative markers are needed to prevent excessive surgery. Neopterin is a new molecule secreted by monocytes and macrophages and indicates the activation of cellular immunity. Therefore it can be used as a marker of immune activation. We aimed to evaluate the diagnostic value of serum neopterin lev...

Introduction: The frequency of new-onset diabetes after transplant (NODAT) is 5–30% in liver transplant recipients. We aimed to analyze the frequency and predictors of NODAT in the patients undergoing liver transplantation (LTx) due to acute liver failure(ALF), and to investigate whether pretransplant hypoglycemia had any effect on NODAT.Materials and methods: Adult patients undergoing LTx due to ALF were analyzed retrospectively. The patients with...

Background: Hashimoto thyroiditis (HT) is the most common autoimmune disease and patients may present different levels of thyroid dysfunction. The association between hypothyroidism and cardiovascular events is well established. However, it remains unclear how mild thyroid dysfunction, autoimmunity and chronic inflammation in HT contribute to an increased cardiovascular risk in euthyroid patients and in subclinical hypothyrodism. Therefore, this study aims to assess insulin re...

Introduction: Studies investigating the association between serum IGF-1, and thyroid nodule, ovarian or thyroid volume in polycystic ovarian syndrome (PCOS) are limited. We aimed to analyze the association between serum IGF-1 level, and ovarian or thyroid volume, or thyroid nodule in PCOS.Materials and methods: The study was performed between June 2017 and August 2019 as prospective design. The patients referred to our medical faculty were included. Adul...

BackgroundPrimary thyroid lymphoma (PTL) is defined as a lymphoma involving only the thyroid gland or the thyroid gland and adjacent (regional) neck lymph nodes. Primary lymphomas of the thyroid are uncommon tumours, representing approximately 5% of the thyroid neoplasms and 2% of extranodal lymphomas. The most characteristic presentation is that of a rapidly enlarging neck mass often associated with dysphagia [5]. The majority of patients are euthyroid ...

Purpose: In previous studies, magnesium (Mg) was found to be lower in cases with more severe primary hyperparathyroidism (PHPT) and higher calcium (Ca) levels. This study evaluated the relationship between serum Mg and serum Ca and phosphorus (P) levels in PHPT and their utility in discriminating osteoporosis and nephrolithiasis.Methods: Patients who were followed up with PHPT between March 2019 and March 2023 were analyzed retrospectively. Biochemical d...

Introduction: Acromegaly is a rare pathological condition characterized by excessive growth hormone (GH) secretion, leading to elevated levels of insulin-like growth factor 1 (IGF-1). According to the 2022 World Health Organization classification, GH-secreting pituitary adenomas fall under the PIT1-lineage. Pure GH-secreting adenomas selectively release growth hormone and may exhibit dense or sparse granulation patterns. Other subtypes include mammosomatotroph adenomas, mature...

Objective: The neutrophil-lymphocyte ratio may increase in Cushing’s Syndrome. We aimed to demonstrate the usability of the neutrophil-lymphocyte ratio in the differentiation of Cushing’s Syndrome and Pseudo-Cushing’s Syndrome, whose differential diagnosis is clinically and laboratory challenging.Material and Methods: 23 patients were included in the study. Patients were divided into Cushing’s Syndrome and Pseudo-Cushing’s Syndro...

Introduction: Targeted therapies and monoclonal antibodies are known to trigger thyroid autoimmunity. No case of autoimmune thyroid disease with mepolizumab, an anti-IL-5 monoclonal antibody, is reported in the literature. In this case report, we present a case of Graves’ disease that recurred after Mepolizumab treatment.Case: A 74-year-old male patient was referred to the endocrinology outpatient clinic upon detection of hyperthyroidism on 11/2021....