Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep1137 | Late Breaking | ECE2023

A diagnostic challenge: Is it metastatic papillary thyroid carcinoma or papillary thyroid carcinoma arising from intramedullar teratoma?

Sakiz Davut , Yılmaz Fatih , Calapkulu Murat

Introduction: Papillary thyroid carcinoma (PTC) distant metastases without regional lymph node metastases are quite rare. Spinal cord teratomas are rare tumors mostly seen in children. To the best of our knowledge, the development of papillary carcinoma in intradural teratomas is theoretically possible, but has not been reported in literature.Case report: A 36-year-old female patient admitted with the complaint of drop foot. On MRI, 20x11x20.5 mm lesion ...

ea0064034 | An unusual case of pubertas tarda: IGSF-1 deficiency syndrome | BES2019

An unusual case of pubertas tarda: IGSF-1 deficiency syndrome

Matthys I , Taes Y , Callewaert B , De Schepper J

Background aim of the work: IGSF-1 encodes a plasma membrane immunoglobulin superfamily glycoprotein that is abundant in the pituitary and testis. Loss-of-function causes an X-linked syndrome which is mainly characterized by congenital hypothyroidism and macroorchidism.[1,2] Because of its relatively recent discovery and its very rare incidence, the time to diagnosis is often long. We present a case of IGSF1 deficiency case where it took 6 years before diagnosis was made. With...

ea0049ep1327 | Thyroid (non-cancer) | ECE2017

Relationship between thyroid volume and baseline vitamin D levels in new-onset graves disease

Yalin Gulsah Y , Cenik Fuat , Celik Huseyin , Kumbasar Abdulbaki

Introduction: Serum 25(OH) vitamin D levels are shown to be significantly lower and associated with lower remission rates in Graves disease. In this study we aimed to investigate the impact of baseline vitamin D levels on thyroid volume in patients with new-onset Graves disease.Materials and methods: This is a monocenter cross sectional study with a total of 61 new-onset Graves disease patients (n:61, F: 40, M:21) who were divided into two groups accordi...

ea0041gp132 | Obesity | ECE2016

The E3 ubiquitin ligase MDM2 acts as a key determinant of hepatic VLDL-triglycerides and ketone body production in obesity

Liu Zhuohao , Xu Aimin , Cheng Kenneth K Y

Introduction: Obesity is a major risk factor for the development of hyperlipidemia and its related cardiovascular complications. Apart from its well-established role in cancer biology, the MDM2-p53 axis has been recently shown to regulate glucose and lipid metabolism. Our preliminary data indicated that MDM2 is dramatically induced in the liver of obese mice. In this study, we aimed to investigate the potential role of hepatic MDM2 in controlling systemic lipid homeostasis usi...

ea0038p30 | Clinical biochemistry | SFEBES2015

Audit of management of patients with hypomagnesaemia in district general hospital

Tofeec K , Pichaipillai L , Bani T , Jostel A , Demssie Y

Background: Hypomagnesaemia is one of the most commonly encountered electrolyte disorders in clinical practice. The reported prevalence of hypomagnesaemia varies from 2.5 to 15% in the general population to as high as 65% among patients admitted to intensive care units. There is a general lack of awareness among physicians regarding the prevalence, clinical significance, and management of hypomagnesaemia.Aim and method: To review current practice of the ...

ea0038p477 | Thyroid | SFEBES2015

Investigating pyrexia whilst awaiting thyroidectomy for Thy 3, Hurthle cell neoplasia

Loumpardia P , Dacruz T , Zeitoun H , Wong S P Y

Thyroid abscess is a rare condition because of the thyroid gland anatomical and biochemical nature. We report a rare case of a rapidly developed thyroid abscess in the background of follicular thyroid nodule.A 77 years old lady admitted for elective right thyroidectomy. She had a history of goiter with normal TFTs. FNA cytology revealed Thy3, Hurthle cell neoplasia. The pre-operation CT scan showed right thyroid large nodule with heterogonous enhancement...

ea0037ep901 | Thyroid cancer | ECE2015

Differentiated thyroid carcinoma in geriatric patients: a single centre experience with 7 years of follow-up

Ozkaya Mesut , Elboga Umut , Eraydin Ayten , Celen Y Zeki

Introduction: We evaluated the characteristics of differentiated thyroid carcinoma in geriatric patients and factors that influenced long-term survival in this retrospective study design. Among 1188 patients with differentiated thyroid carcinoma who were treated at our institution over the past 7 years, 144 patients were identified who were age 65 years or older(age range:65–88 years) at the time of their initial diagnosis. This study conducted a retrospective analysis of...

ea0070aep826 | Reproductive and Developmental Endocrinology | ECE2020

Assessment of the status of the pituitary-gonadal axis in men who have been using androgenic anabolic steroids for a long time

Lykhonosov Mykola , Babenko Alina Y. , Makarin Viktor A. , Fedotov Yuri N

Background: The study of the state of the pituitary-gonadal axis (PGA) in users of anabolic androgenic steroids (AAS) is important. The severity of inhibition of luteinizing (LH), follicle-stimulating (FSH) hormones, total testosterone (Tt), inhibin B may depend on the type of AAS used, its doses, the simultaneous use of several types of AAS and the duration of their administration.Aim: To evaluate the levels of LH, FSH, Tt and Inhibin B depending on the...

ea0070ep223 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

The relationship between milk and dairy consumption and obesity in children between the ages of 7–10

Mantar Ferhan , Yılmaz Bușra

Introduction: There is some evidence shows daily consumption of milk/dairy products prevents obesity and many diseases. Even in adulthood, the consumption of adequate milk/dairy products in childhood is protective of obesity. Therefore, balanced consumption of milk/dairy products is thought to prevent obesity or overweight, which is an important health problem nowadays. In our study, we aimed to determine whether there is a relationship between the consumption of milk/dairy pr...

ea0029s35.2 | Endocrinology and the Olympics: Will hormones help to win? | ICEECE2012

Can an endocrine patient participate in high performance sports?

Auchus R. , Brenna J. , Tobias H. , Zhang Y.

The question posed by this title encompasses three issues. First, certain endocrine diseases present physiologic challenges to high-intensity or endurance activities, including type 1 diabetes mellitus and adrenal insufficiency. Using carefully adjusted insulin regimens evolved in concert with training sessions, several athletes with type 1 diabetes have succeeded in elite competitions, but the endocrinologist must ‘train with the athlete’ and craft regimens that con...