Endocrine Abstracts (2002) 3 P20

A rare cause of intrasellar mass: Cholesterol granuloma

F Kelestimur1, K Unluhizarci1, R Colak1, S Balkanli2, IO Karahan3, A Selcuklu4, F Ozturk2 & F Bayram1


1Department of Endocrinology, Erciye University, Kayseri, Turkey; 2Department of Pathology, Erciyes University, Kayseri, Turkey; 3Department of Radiology, Erciyes University, Kayseri, Turkey; 4Department of Neurosurgery, Erciyes University, Kayseri, Turkey.


The most common cause of a mass lesion in the sella is pituitary adenoma. Some parasellar lesions may be cystic and sometimes may mimic the clinical and radiological features of pituitary adenoma. A 36 year-old woman was admitted to the hospital because of headache for five years and amenorrhoea for five months. Magnetic resonance (MR) imaging of the pituitary gland showed sellar mass lesion characterized by high signal intensity on T1 and T2-weighted images. Endocrinological investigations revealed gonadotrophin, GH and ACTH deficiencies. She was operated on by transsphenoidal approach and the histopathologic diagnosis was compatible with cholesterol granuloma. Cholesterol granuloma of the sella is not a well-described entity and may be due to a hemorrhage within the pituitary adenoma or it is a distinct form of craniopharyngioma.

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