Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 10 | SFE2005 | Next issue

196th Meeting of the Society for Endocrinology and Society for Endocrinology joint Endocrinology and Diabetes Day

Special Interest Groups

Big issues in pituitary research

ea0010s30 | Big issues in pituitary research | SFE2005

Steroidogenic factor-1 (SF-1) and DAX-1

Achermann J

The past decade has seen significant advances in our understanding of the molecular mechanisms of pituitary development and function. However, relatively few gonadotrope specific factors have been identified to date. Through characterization of patients with endocrine disorders as well as transgenic mice, it has emerged that the nuclear receptor transcription factors SF-1 and DAX-1 play an important role in the regulation of gonadotrope activity. SF-1 (NR5A1) activates multipl...

ea0010s31 | Big issues in pituitary research | SFE2005

Folliculostellate cells: what are they?

Rees D

Pituitary folliculostellate (FS) cells were originally described in 1953 and comprise up to 10% of the anterior pituitary cell population. These epithelioid cells are thought to be derived from neuroectodermal cells and express S-100, a nervous tissue-selective protein that is used to define FS phenotype. Unlike their endocrine counterparts, they are devoid of secretory granules and were considered non-secretory until relatively recently. Experiments using pituitary slices hav...

ea0010s32 | Big issues in pituitary research | SFE2005

Lymphocytic hypophysitis

Aylwin S

Lymphocytic hypophysitis (LYH) is an unusual pituitary disorder in which an inflammatory process compromises normal anterior and posterior pituitary function, and produces a mass effect on adjacent structures....