Endocrine Abstracts

We recently generated a transgenic reporter mouse, named ERE-Luc, to study the transcriptional activity of estrogen receptors (ERs) in patho-physiological states and showed that in this model system the synthesis of luciferase is strictly associated with an augmented transcriptional activity of both ERα and ERβ receptors but is independent from the activity of receptors related to ERs. Studies on ER activity in sexually mature, adult female mice showed that in cyclin...

A Maggi, Center of Excellence on Neurodegenerative Diseases, University of Milan, Via Balzaretti 9, Milan, Italy Abstract Professor Adriana Maggi’s career has been devoted to the study of the activities of estrogens, initially in the central nervous system and, more recently, in other non-reproductive organs with the aim to understand the physiological importance of this hormone beyond the control of reproductiv...