Searchable abstracts of presentations at key conferences in endocrinology
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8th European Congress of Endocrinology incorporating the British Endocrine Societies

Poster Presentations

Comparative endocrinology

ea0011p211 | Comparative endocrinology | ECE2006

The patients with HIV lipodystrophy syndrome have lower total fat mass but similar free fat mass

Freitas P , Carvalho D , Correia F , Faria T , Perez B , Marques R , Serrão R , Pereira J , Mota Miranda A , Medina JL

Introduction: The highly active antiretroviral therapy (HAART) completely changed the natural history and body composition of the infected patients. The lipodystrophy syndrome of HIV-infected patients (IP) is characterized by fat mass redistribution in the limbs, face lipoatrophy and abdominal lipohypertrophy. Dual-energy x-ray absorptiometry scan (DEXA) and bioelectrical impedance (BIA) are techniques to determine body composition (BC).Aims: Evaluate th...

ea0011p212 | Comparative endocrinology | ECE2006

Dynamic macroprolactin and adjusted prolactin responses in hyperprolactinaemic patients

Bandyopadhyay S , Diver MJ , Vora JP

Background: Prolactin is found in serum in different molecular forms, differing in molecular size. Macroprolactin is a complex of prolactin with immunoglobulin and has limited biological activity due to failure to cross capillary wall because of its high molecular weight complex.Objective: To assess the response of the inactive macroprolactin and the biologically active monomeric prolactin, in patients with hyperprolactinaemia, during TRH and metoclopram...

ea0011p213 | Comparative endocrinology | ECE2006

Retrospective study of usefulness of Sestamibi scan in primary hyperparathyroidism

John K , Blackburn S , Miell J , Diaz C

Background and Aims: Primary Hyperparathyroidism is fairly common and the diagnosis is established by demonstrating raised blood parathormone levels in the presence of hypercalcemia. Sestamibi scan is an investigation used primarily to identify the offending gland which would help in surgery. The aim of this study was to assess the usefulness of sestamibi scan in Primary Hyperparathyroidism.Method: Case notes for patients with Primary Hyperparathyroidism...

ea0011p214 | Comparative endocrinology | ECE2006

Assessment of oxidative stress in patients with polycystic ovarian syndrome treated with either Orlistat or Metformin

Shepherd J , Jayagopal V , Kilpatrick ES , Atkin SL

Orlistat and Metformin have both been shown to be beneficial in the treatment of Polycystic Ovarian Syndrome (PCOS), however, because Orlistat works by decreasing the absorption of dietary lipids, there is the potential to decrease absorption of lipophilic antioxidant substances with consequent decreased protection from oxidative stress. The objective of this study was to evaluate and compare the effect of treatment with orlistat vs. metformin on oxidative stress in pat...

ea0011p215 | Comparative endocrinology | ECE2006

Prognostication in canine parvoviral diarrhoea using basal serum cortisol concentrations

Schoeman JP , Venter LJ , Goddard A , Leisewitz AL , Herrtage ME

In human critical care, patients with the highest cortisol concentrations generally have the highest mortality rates, with resultant prognostic classifications based on basal cortisol and/or delta cortisol concentrations. In contrast, comparative data on canine critical illness does not exist. Parvoviral diarrhoea is a severe infectious disease inducing a sepsis-like state predominantly in paediatric canine patients. The objective of this study was to evaluate the prognostic v...

ea0011p216 | Comparative endocrinology | ECE2006

Short-term effects of propionate on the leptin system and on G protein-coupled receptor GPR41 mRNA levels in adipose tissue of goats

Mielenz MM , Seybold CS , Sauerwein HS

Propionate upregulates leptin synthesis through the G protein-coupled receptor 41 (GPR41) in mice. In contrast to monogastric mammals, ruminants almost entirely depend on short chain fatty acids as energy source, but the reports about the physiological relevance of propionate for leptin secretion in these species are controversial and the importance of the GPR41 for its regulation is not yet clarified. Here we characterise the effects of intravenously infused propionate on the...

ea0011p217 | Comparative endocrinology | ECE2006

Ontogeny of galanin and vasotocin immunoreactivity in the supraoptic nucleus (SON) and the bed nucleus of the stria terminalis (BSTM) in chickens

Klein S , Grossmann R

Vasotocin (AVT), the avian homolog of vasopressin, is synthesized in the BSTM of chickens in addition to the hypothalamo hypophysial axis. In previous reports, sex specific AVT–immunoreactivity(ir) in male BSTM (Jurkevich et al. 1999) and it’s ontogeny were demonstrated (Grossmann et al. 2002). In addition, galanin (Gal) was found in male BSTM co-localized to AVT. In the present study, the ontogeny of AVT- and Gal-ir was investigated in the SON as part ...