Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2006) 11 P787

ECE2006 Poster Presentations Thyroid (174 abstracts)

Epidemiologic analysis of thyroid fine needle aspiration biopsies over a period of 18 years (1987-2004)

S Polyzos 1 , M Kita 1 , DG Goulis 1 , A Benos 2 , N Flaris 3 , M Leontsini 3 & A Avramides 1


1Department of Endocrinology, ‘Hippocration’ General Hospital, Thessaloniki, Greece; 2Laboratory of Hygiene, Medical School, Aristotle University, Thessaloniki, Greece; 3Laboratory of Pathology, ‘Hippocration’ General Hospital, Thessaloniki, Greece.


Introduction: Fine Needle Aspiration Biopsy (FNA) is a method widely used in the assessment of thyroid nodules. The main aim of this 18-year retrospective study was the investigation of the diagnostic value of FNA in the approach of thyroid malignancy.

Subjects and methods: patients underwent 1938 FNAs from 1987 to 2004 in the Department of Endocrinology, ‘Hippocration’ General Hospital, Thessaloniki, Greece. 178 of these patients subsequently underwent total or subtotal thyroid resection and a pathology report was available.

Results: Pathology reports are the ‘gold standard’ for the diagnosis of thyroid malignancy. FNA shows a sensitivity of 76.2% and a specificity of 90.5%, with a significant degree of agreement between the two methods (Cohen’s method, P<0.05). There was a considerable improvement in the diagnostic value of FNA during the sub-period 1996–2004 as compared to the sub-period 1987–1995, probably due to increased experience of the persons performing and interpreting the FNA.

Conclusions: (1) FNA is a reliable diagnostic method in the initial assessment of thyroid malignancy, (2) a non-diagnostic FNA should always be repeated, (3) even after a cytological diagnosis of benign hyperplasia, meticulous follow-up is necessary and (4) increased experience of the persons performing or interpreting the FNA leads in improvement in the diagnostic value of FNA in the approach of thyroid malignancy.

Volume 11

8th European Congress of Endocrinology incorporating the British Endocrine Societies

European Society of Endocrinology 
British Endocrine Societies 

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