Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2006) 11 P9

ECE2006 Poster Presentations Bone (46 abstracts)

Bone mineral density in patients with type 1 diabetes

Elen Giorgadze , Marina Tsagareli , Nino Jikurauli & Nino Svani


N4 clinical hospital, Tbilisi, Georgia.


Background: Type1 diabetes is associated with reduction in Bone mineral density (BMD). It is thought, that metabolic abnormalities associated with type 1 diabetes alter the BMD, but the pathologic mechanisms of reduced bone mass are not fully understood.

Objective: The aim of our study was to reveal whether the metabolic control affects bone mass in patients with type 1 diabetes.

Materials and Methods: We studied 80 patients (45 -male, 35 -female) with type1 diabetes. The inclusion criteria were duration of diabetes 20–25 years.

We measured HbA1C, ionized calcium, phosphorus values, parathyroid hormone (PTH), osteocalcin (OC), BMD with ultrasound bone densitometry.

Results: The mean value of HbA1C was 6.8 mcm/frghb, the mean value of BMD was (−2.1±0.01), Ca++(1.05±0.01 mmol/l) and OC (6.1±0.02 ng/ml) values were near to the lower norm, PTH was at the upper level of the norm (58.3±0.01 pg/ml).We revealed the linear correlation between the BMD and HbA1C levels (r=0.42, P<0.05) and the duration of disease.(r=0.45, P<0.01).

Conclusions: Duration of diabetes and poor metabolic control were the main determinants affecting bone mass. Optimization of metabolic control is required to prevent osteoporosis.

Volume 11

8th European Congress of Endocrinology incorporating the British Endocrine Societies

European Society of Endocrinology 
British Endocrine Societies 

Browse other volumes

Article tools

My recent searches

No recent searches.

My recently viewed abstracts