Endocrine Abstracts (2006) 11 P318

Cardiovascular risk factors and macrovascular complications in type 2 diabetes

Karima Khiari, Hela Cheikhrouhou, Insaf Hadj Ali & Nejib Ben Abdallah


Charles Nicolle Hospital, Tunis, Tunisia.


The frequency of type 2 diabetes increases in all of the world. The risk for atherosclerosis vascular disease is greatest in type 2 diabetic patients who have other known risk factors such obesity, smoking, hypertension and dyslipidemia.

The aim of our study is to determine the frequency of cardiovascular risk factors associated to diabetes and the frequency of macrovascular complications in type 2 diabetic patients.

It is a retrospective multicentric study of 708 patients (375 (53%) women and 333 (47%) men) in 7 departments of diabetes in Tunisia.

Results: The mean age of patients is 58.8±11.6 years.

Cardiovascular risk factors: Obesity is showed in 32.8% of patients, fat android distribution is noted in 92.5% and smoking in 68.5% of patients. Hypertension is confirmed in 59.1% of patients, 31.9% of patients have hyper triglyceridemia and 26.8% have hypercholesterolemia

Macrovascular complications: Coronary insufficiency showed in 17.6% % and myocardial infarction in 3.7% of patient. Arteritis of lower lumbs is noted in 16.6% of patients and amputation in 4.3%.

Our study confirmed that type 2 diabetic have frequently several cardiovascular risk factors associated to the diabetes. All this factors should be considered in the treatment of type 2 diabetic patients to reduce complications.

Early insulintherapy is recommended to improve glycemic control. Management of type 2 diabetes must be global including treatment of all cardiovascular risk factors.

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