Objective of the study: To determine the prevalence of thyroid tissue changes in mild iodine deficiency region.
Materials and methods: The 17-th month-lasting study was carried out in Moscow colleges, factories and offices. 1520 people (1403 female, 117 male) median age 34 years were screened by thyroid ultrasonography with liner probe 7,5 MHz.
Results: Thyroid ultrasound disorders have been demonstrated to be high prevalent in women 37.6% (527/1403) vs men 13.7% (16/117). As a male cohort was not large enough, only female screening results were evaluated. Nonpalpable focuses of thyroid tissue under 1 cm in diameter were found in 12.5% (176 patients). Thyroid nodules larger than 1 cm were observed in 10.3% (144/1403) patients, 88 (6.3%) had solitary thyroid nodules, 56 (4.0%) had multinodular goiters. Diffuse hypoechogenic thyroid tissue was found in 8.7% (122) patients. Diffuse goiter (with normal echogenic tissue) was revealed in 6.1% (85) patients.
Conclusion: In Moscow (mild iodine deficiency region) the overall prevalence of ultrasound thyroid abnormalities were found 37.6%. We revealed that nonpalpable focuses of thyroid gland under 1 cm are the most prevalent pattern (12.5%) in all age groups. Our study confirms the common established trend: the relative decrease of diffuse goiter prevalence in comparison with nodular goiter (with multinodular goiter predominance) in eldery people (>45 years old).
01 - 05 Apr 2006
European Society of Endocrinology