Endocrine Abstracts (2006) 11 P927

Epidemiology of thyroid cancer in Republic of Sakha during 1970–2001

Albert Makarov, Elena Makarova, Valery Argunov & Fenya Ivanova

National Centre for Medicine, Yakutsk, Republic of Sakha, Russia.

Exposure to ionising radiation, changing levels of iodine nutrition, and increased pathologic diagnosis of clinically unimportant thyroid neoplasm have all been proposed as explanations for a world-wide rise in the incidence of thyroid carcinoma over the past 6 decades. Yakutia is geographically an area of endemic iodine deficiency (the population is about 1 million). According to previous research in the endemic areas there are more occasions of follicular thyroid cancer, whereas in the areas free from iodine deficiency – papillary cancer. Additionally, radioinduced thyroid cancers also belong to the same histological form – papillary cancer.

Aim of our study was to present evaluate the epidemiology of the new cases of thyroid in population of Republic of Sakha (Yakutia) during 30 years, stating from 1990 and up to 2000.

Materials and Methods: We traced all new cases of thyroid cancer in the whole Republic of Sakha.

Results: The statistics by each year of the study are shown in the table:

During the period of study the number of new cases raise from 5 in 1970 to 44 in 2001.

Conclusion: Epidemiology of thyroid cancer in Republic of Sakha shows rapidly significantly increased incidence during last 32 years. Prevailing papillary cancer among the population of the endemic area (Republic of Sakha) may be connected with unfavorable ecological situations in this region.

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