Endocrine Abstracts

The gonads and adrenal cortex are the tissues producing steroid hormones such as sex steroids, mineralocorticoid and glucocorticoid. These steroids are synthesized by consecutive enzymatic reactions by P450s and hydroxysteroid dehydrogenases. Studies of the tissue specific expression of these gene involved in steroidogenesis identified an orphan nuclear receptor Adrenal-4-Binding Protein (Ad4BP, NR5A1), also known as Steroidogenic Factor-1 (SF-1). In addition to these steroido...

K Morohashi, National Institute for Basic Biology, Okazaki, Japan. AbstractKen Morohashi received a PhD from the Department of Biology, Graduate School of Science, Kyushu University in 1986. After studying regulation of steroidogenic genes with Prof. Omura, he was invited as a professor of the Division of Sex Differentiation by the National Institute for Basic Biology, National Institutes for Natural Sciences in 1996. ...