Endocrine Abstracts

PCOS is a complex genetic disease resulting from the interplay between susceptibility genes and environmental factors. Hyperandrogenemia consistent with an alteration in ovarian and adrenal steroidogenesis is the major reproductive phenotype in families of women with PCOS, including mothers and brothers. Reproductive age sisters have two affected phenotypes: (1) hyperandrogenemia and chronic anovulation or (2) hyperandrogenemia with regular menses and apparently normal fertili...

Andrea Dunaif, Northwestern University, Feinberg School of Medicine, Chicago, United States. AbstractDr Dunaif received her MD from Columbia University College of Physicians and Surgeons, trained in New York and Boston and rose to rank of Associate Professor at the Mount Sinai School of Medicine. Since 1992 Dr Dunaif has held posts at Brigham and Women’s Hospital as Director of Women’s Health and Chief of the...