Searchable abstracts of presentations at key conferences in endocrinology
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9th European Congress of Endocrinology

Plenary Lectures

The coordination of circadian time in brain and peripheral organs

ea0014pl5 | The coordination of circadian time in brain and peripheral organs | ECE2007

The coordination of circadian timing in brain and peripheral organs

Schibler Ueli , Kornmann Benoit , Saini Camille , Reinke Hans , Schaad Olivier , Dibner Charna

The mammalian circadian timing system influences most physiology, including sleep-wake cycles, cardiovascular activity, body temperature, renal plasma flow, intestinal peristaltic, metabolism, xenobiotic detoxification, and many endocrine functions. Circadian pacemakers were originally believed to exist only in a few specialized cell types, such as neurons of the suprachiasmatic nucleus (SCN). However, this view has been challenged by the discovery that self-sustained and cell...