Endocrine Abstracts (2008) 16 P251

Frequency of hypertension studied by ambulatory blood pressure monitoring in type two diabetes

Katherinne Garcia-Malpartida, Jesus Yanini-Garcia, Celia Bañuls-Morant, Eva Sola-Izquierdo, Carlos Morillas-Ariño, M Luisa Martinez-Triguero & Antonio Hernandez-Mijares


Endocrinology Service, Hospital Universitario Dr Peset, Valencia, Spain.


Objectives: To know the frequency of hypertension in a group of males with type two diabetes without the antecedent of hypertension, by means of ambulatory blood pressure monitoring (ABPM). To assess the possible differences between the subjects with and without hypertension in age, time of duration of diabetes, obesity and the features of metabolic syndrome.

Methods: We included consecutively 55 males with type two diabetes without the antecedent of hypertension. We made an anthropometric and analytic evaluation and an ABPM during 24 h. For the diagnostic of hypertension we used the ‘VII Report of the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure’. For the diagnosis of metabolic syndrome we used the ‘NCEP ATP III guidelines’.

Results: We detected high blood pressure in 20 patients (36.4%). The most part (50%) had elevated systolic and diastolic rates, 35% only systolic and 15% diastolic. The blood pressure reduction during sleep was different between the groups with and without hypertension: dipper (62 vs 20%), non dipper (60 vs 32%) and riser (20 vs 6%), χ2 P=0.01. The patients with hypertension had metabolic syndrome in 90% vs 48% of the patients without it (χ2 P<0.01).

Conclusions: One third of diabetic patients without antecedent of hypertension had it, discovered with ABPM. The most common was the increment of both systolic and diastolic. The blood pressure reduction during sleep was pathologic in 80% of patients with hypertension and 33% without it. The most part of the patients with high blood pressure had metabolic syndrome.

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