Endocrine Abstracts

Postmenopausal hormonal therapy has been used to manage climacteric symptoms since the 1950’s. Several large observational studies suggested that the use of HRT may also have a role in the prevention of chronic conditions in the postmenopausal woman. In a Department of Health survey performed in 1998, 38% of women in England aged 45–54 years had used HRT. However over the past few years there has been a marked fall in prescribing rates due to the publication of sever...

A 28-year-old lady who was born with ambiguous genitalia. A decision was made to rear the patient as male, and was subsequently registered as a boy. Investigations demonstrated a chromosomal mosaic pattern 45XO/46XY fitting the category of mixed gonadal dysgenesis. Internal organs were more suggestive of a female type: uterus, vagina, and fallopian tubes, gonads were variable but typically an ovary on one side and a testis on the other. HCG test showed a brisk rise in serum te...

‘HM’ 39-year-old.TAH & BSO 1 year ago for mennorhagia and endometriosis, at another hospital. No serious pathology.Patient c/o hot flushes, lethargy, mood swings and low libido.Treated by GP for frequent migraines but no visual problems.Family h/o Cardio-Vascular disease;Grandfather MI RIPFather MI Alive & well<p class=...

Abstract not available....

Forty-four-year-old transgender – female to male who underwent surgery for gender reassignment including hysterectomy, oophrectomy and mastectomy.He has been on testosterone replacement since 2003, initially oral, then sustanon 250 mg IM injection 2 weekly which was self-administered. He was keen on long-acting testosterone injections (Nebido) so was referred to our endocrine service, as his GP was reluctant to prescribe testosterone replacement, as...