Endocrine Abstracts (2009) 20 ME1

How to optimize the management of thyroid associated orbitopathy

P Perros

Department of Endocrinology, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.

Thyroid associated orbitopathy affects approximately a third of patients with Graves’ disease. It is responsible for significant symptoms, poor quality of life, and if neglected can cause blindness. Early diagnosis of Graves’ ophthalmopathy is paramount as is early detection of sight-threatening disease. All but the mildest cases are best referred to centres who provide multidisciplinary care and have the experience and expertise on managing this condition. Treatment must be tailored to the individual and timed appropriately. The mainstay of medical treatment is high dose steroids. Orbital irradiation has a role in pateints with dysmotility. Surgical treatment has a lot to offer in patients with sight-threatening disease and to improve functional and cosmetic outcomes.

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