Endocrine Abstracts

Overt hypothyroidism, diagnosed and treated with L-thyroxine pre-pregnancy, affects 1% of pregnancies. Untreated maternal hypothyroidism is associated with adverse obstetric and neonatal outcomes, and even when partially treated the risks of miscarriage and prematurity remain elevated compared to euthyroidism. With increased understanding of the normal physiological changes to thyroid function during pregnancy, there should be a predictive approach to thyroxine ...

Clinical hyperthyroidism is not uncommon in pregnancy, with a reported prevalence of 0.1–0.4%, and is caused most frequently by Graves disease. Careful monitoring of thyroid function is critical in preventing the many potential complications that can occur in pregnancies of mothers with hyperthyroidism. Maternal complications include hypertension, thyroid storm, heart failure preterm labour, and placental abruption. Foetal and neonatal complications include stillbirth, in...

The manifestation of adrenal disorders during pregnancy is a rare but regularly occurring event and can pose significant problems for the involved medical professionals. This lecture will give an overview of the major management issues surrounding disorders of the adrenal cortex during pregnancy. This includes the requirements for the adjustment of corticosteroid replacement therapy in adrenal insufficiency, due to the physiological changes in corticosteroid secretion during p...

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