Papillary thyroid carcinoma (PTC) is most frequent endocrine cancer on the other hand papillary microcarcinoma can be seen increasing frequency in recent years. In this study we compare clinical and histopathological characteristics of thyroid papillary microcarcinoma and papillary thyroid carcinoma retrospectively.
Eighty one PTC and 38 PMC total 119 patients followed between 2005 and 2009 were enrolled study. Average follow-up time is 35 months in PTC and 36 months in PMC. Age, sex, background, tumour variants, pathological features, surgical procedure and postoperative surgical complications were collected and analysed from archive records.
There were no significant difference between PTC and PMC patients for prognostic factors like capsul invasion, vascular invasion, lymph node metastasis, distant metastasis, bilaterality, multicentricity, age, sex and tumour variants(P>0.05). Lymph node metastasis was more frequent in bilateral and multicentric tumours (P<0.05).
As a result we found no significant difference between PTC and PMC for poor prognostic factors like capsul invasion, vascular invasion, lymph node metastasis, distant metastasis, bilaterality and multicentricity. According to these findings follow-up and therapy for PMC is processed like PTC.