Endocrine Abstracts

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Obesity and DM2 increasingly affect young adults worldwide, to the point of warranting the description of ‘epidemic’. This means that greater numbers of women of reproductive age are at risk. Frequently DM2 remains undiagnosed until pregnancy. The rate of congenital malformations seems to be the same with that of women with DM1, but the rate of perinatal mortality appears to be increased, according to a recent meta-analysis. These findings occur despite the fact that...

To adapt the working of the thyroid to the changes occurring during pregnancy, an adequate availability of iodine and the integrity of the thyroid gland are needed. With regard to thyroid function assessment during pregnancy, is it important to be aware of the differences in accuracy of the different FT4 assays. Thyroid autoimmunity (TAI) is the most common cause of hypothyroidism before and during pregnancy and many women with TAI and a normal thyroid function in e...