Endocrine Abstracts

The medical and social importance of a problem of a gestational diabetes (GD) is caused by higher probability of occurrence of the complicated current of pregnancy and delivery. Frequency of a GD varies within 1.5–13% from total pregnancies, essentially increasing in risk groups.

Materials and methods: One hundred and fifty-six pregnant women in different periods of gestation were examined. The estimation of GD’s risk factors was spent to all women. Low risk was revealed in 7 women, medium – in 43 pregnant women, high – in 62 patients. 75-g OGTT was spent between 24 and 28 weeks’ gestation to women at low and medium GD risk. Women at high risk of GD were screened using the 75-g OGTT at first antepartum visit.

Results: GD was diagnosed in 10/156 (15.6%) in women at high risk for GD. Fasting glucose level in women with GD was 5.4±1.7 vs 4.8±0.4 mmol/l in women without GD (P=0.293). Two-hours glucose level in women with GD was 8.3±1.4 vs 5.5±1.2 mmol/l in women without GD (P=0.001). GD was diagnosed in 42/146 (28.7%) women at low and medium risk for GD. Fasting glucose level in GD group was 4.9±0.6 vs 4.6±0.6 mmol/l in women without GD (P=0.005). Two-hours glucose level in GD group – 8.9±0.9 vs 5.8±1.2 mmol/l in women without GD (P=0.001). 45.2% of GD women had parents with diabetes versus 26.3% women without GD (P=0.024). Other risk factors for GD statistically didn’t differ among groups.

Conclusion: GD prevalence at pregnant women has made of 15.6%. In group with high risk for GD should be included pregnant with singular risk factor – burdened heredity on a diabetes.