Endocrine Abstracts (2011) 26 P406

Cytological evaluation of pyramidal lobe and thyroglossal duct cysts

Ayten Oguz, Husniye Baser, Dilek Tuzun, Alper Usluogullari, Ali A Tam, Reyhan Ersoy, Gulnur Guler & Bekir Cakir


Ataturk Education and Research Hospital, Bilkent, Ankara, Turkey.


Aim: Thyroid pyramidal lobe and thyroglossal duct cysts were reported to be associated with increased risk of thyroid cancer. In this study, we aimed to evaluate ultrasonography (US) guided fine needle aspiration biopsy (FNAB) cytology results of pyramidal lobe and thyroglossal duct cysts.

Material and methods: Patients with pyramidal lobe and thyroglossal duct cysts detected in US were included. Thyroid functions, thyroid autoantibodies, Tc 99m thyroid scintigraphy and US guided FNAB cytology results were evaluated.

Results: There were 79 (97.5%) female and 2 (2.5%) male patients with a mean age of 52.0±12.3 (20–82). Thyroglossal duct remnant was observed in 26 (32.1%) and pyramidal lobe in 55 (67.9%) patients. There were 74 (91.4%) patients with a previous history of thyroidectomy and all were histopathologically benign. In 7 patients, there was not a history of thyroid operation. FNAB results of all thyroglossal duct and pyramidal lobe were benign.

Conclusion: Pyramidal lobe is an embryological remnant of thyroglossal duct and its incidence varies between 15 and 75% in surgical and autopsy series. It was reported that this tissue becomes hypertrophic under the influence of increased thyrotrophin in thyroidectomized patients. Thyroglossal duct cysts develop in front of the neck. Increased risk of occult malignancy risk was reported in solid lesions, particularly when they include ectopic thyroid tissue. In our series, we did not observe any malignant cytology result.

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