Endocrine Abstracts (2011) 26 P495

Overweight and risk for osteoporosis

Snezana Polovina1, Klara Tucic Nemet1, Jelena Micic2, Koviljka Milenkovic Vulovic3, Dusan Micic4 & Dragan Micic5


1General Hospital Subotica, Subotica, Serbia; 2Clinic for gynecology and obstetrition, Clinical Center of Serbia, Belgrade, Serbia; 3Medical Center Cacak, Cacak, Serbia; 4Emergency Center, Clinical Center of Serbia, Belgrade, Serbia; 5Clinic for endocrinology, diabetes and metabolic disease, Clinical Center of Serbia, Belgrade, Serbia.


BMI over 30 kg/m2 is associated with lowest risk for osteoporosis and hip fracture in both sex. Increased body fat mass is followed with greater hip fracture risk, independently of BMI.

Aim: Evaluate risk for osteoporosis in postmenopausal female with BMI 25–29.9 kg/m2 and influence of body fat mass on mineral bone density in overweight women.

Material and methods: One hundred postmenopausal female, age 48–88 (62.8±12.3), divided in two groups: group A, BMI 20–24.9 kg/m2 (N=19) and group B, BMI 25–29.9 kg/m2 (N=81) and according of body fat mass on group A1 with <30% fat mass (N=4), and B1 with more than 30% fat mass (N=96). Mineral bone density (femoral neck) percentage of body fat mass was measured by DEXA. Break point for osteoporosis was −2.5 S.D.

Results: In group B bone mineral density was more than group A (χ2=10.17, P=0.0014 with correction for continuation χ2=7.96, P=0.0048). Between A1 and B1 there was no differency according osteoporosis appearance (χ2=0.42, P=0.5176 with correction for continuation χ2=0.01, P=0.9297).

Conclusion: Postmenopausal female with BMI from 25 to 30 kg/m2 have more mineral bone density than normal weight female, and lower risk for osteoporosis. Percentage of body fat mass 30–51% in overweight post menopausal female has no influence on bone mineral density.

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