Endocrine Abstracts (2011) 26 P522

Relationship between benign calcification of breast and lumbar bone mineral density

J H Lee


Dongeui Medical Center, Busan, Republic of Korea.


Introduction: There are many reports that vascular and/or heart valve calcification is good predictor for low bone mineral density. I investigated whether benign calcification of breast can also well predict low bone mineral density.

Methods/design: I have reviewed and analyzed the records of 91 women with age more than 50 years old among patients examined bone mineral density and breast mammography from January through December 2010. The lowest value of lumbar bone mineral density was selected and analyzed, but femoral bone mineral density was not analyzed due to no routine examination and frequent omission.

Results: On breast mammography, benign calcification was observed in 21 patients (group A) and was not observed in 70 patients (group B). Lumbar bone mineral density was 0.832±0.150 g/cm2 on the average with benign calcification and 0.782±0.141 g/cm2 without benign calcification. There was not a significant difference between group A and B (P=0.169). Average age of patients of group A and B was 59.9±6.1 years and 61.1±5.8 years respectively, which had no significant difference (P=0.4). In addition, there was not a significant difference between group A and B for body weight, body mass index, waist circumference, smoking habitus, alcohol drinking habitus and physical activity index (P>0.05).

Conclusion: Lumbar bone mineral density with benign calcification on breast mammography was not statistically different compared to that without calcification. In the future there is a need for prospective, greater mass study.

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