Endocrine Abstracts (2011) 26 S11.2

Clinical aspects of Klinefelter syndrome in childhood, adolescence and adulthood

Anders Juul


Department of Growth and Reproduction GR, Rigshospitalet section 5064, Blegdamsvej 9, DK-2100 Copenhagen Ø, Denmark.


Klinefelter syndrome (KS) which affects 1–2- per 1000 males, is not only challenging for the patients and their families. Professionals, who manage KS patients need a much better scientific foundation for decision making in patient care. Surprisingly little research on how to manage boys, adolescents and men with KS has been carried out in comparison to management of other clinical problems like, e.g. Turner syndrome. One of the problems has been that management, which must be a live long process in KS, most often is split between paediatricians, who take care of the boys with KS, and andrologists and endocrinologists who manage fertility problems and androgen insufficiency later in life. However, to obtain knowledge on the full spectrum of the syndrome, and the needs for intervention we should have life-long perspective from birth to old age in mind when we make our treatment strategies.

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