Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2012) 28 N2.2

SFEBES2012 Nurse Session Addison';s/ phaeochromocytomas/Conn's Syndrome (5 abstracts)

Abstract for paraganglioma case presentation at Nurses session at 19–22 March 2012

Philip Yeoh


Endocrinology & Diabetes, The London Clinic, London, United Kingdom.


24 years old gentleman presented with 6 months history of nausea and occasional vomiting after eating, night sweats and pain on left side of abdomen. CT abdomen and pelvis showed left sided retroperitoneal mass measuring 6.3×5.8×8 cm with lying BP 120/100 and standing 140/100 pulse 100 per min Urinary noradrenaline was 27732 nmol/24hour. Repeat urine noradrenaline shown 12479 nmol and 13505 nmol/24hr. MIBG showed tumour on left upper abdomen with no uptake in the lungs and liver. Tumour markers were negative but growth hormone 62 mU/l. Commenced on phenoxybenzamine 10 mg QDS propranolol 80 mg TDS prior to surgery. Paraganglioma was removed in Sep 2002. Symptoms disappeared and BP to 108/66 pulse 66. Gene analysis showed no known variant for hereditary syndromes Oct 2004 urine cats elevated (614 nmol) again to above upper limit of normal (560 nmol/24 hr) CT showed multiple tiny pulmonary nodules. 200 mCi M131IBG therapy was given successfully tail-end scan showed weak uptake of MIBG in mid thorax, right hilum and liver. CT scan of Chest in April 2005 showed no change in lesions. Lost contact for 17 months, went travelling and then returned with plasma noradrenaline 36924, Normetanephrine 16900 (1000–2000), urine noradrenaline 7721 (160–485). MIBG & Isotope bone scanning shown presence of metastases in skull, sternum and 3rd lumber vertebral. M131IBG therapy was given again in 2007 and chemotherapy of Temozolomide (2007), CCNU (Lomustine) couple with Capecitabine (2008), Cisplatin and Etoposide (2009), radiotherapy in 2010. Reviews were carried 1–3 monthly. Unfortunately patient lost the battle in Jan 2011. This presentation will look at patient’s journey and his battle with a neuroendocrine tumour. Both consultants and nurses were able to provide support that was needed for patient and family. Nurses role was to provide support, counselling, contact points, patient education and follow up tests.

Declaration of interest: There is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported.

Funding: No specific grant from any funding agency in the public, commercial or not-for-profit sector.

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